The evolutionary mechanisms leading to duplicate gene retention are well understood. but the long-term impacts of paralog differentiation on the regulation of metabolism remain underappreciated. Here we experimentally dissect the functions of two pairs of ancient paralogs of the GALactose sugar utilization network in two yeast species. We show that the Saccharomyces uvarum network is ... https://chefesquipmenters.shop/product-category/ladders/